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HRID350987

反应详情

EQUATION

反应方程式

HRID 350987 的结构方程式

REACTANTS

反应物

4
结构：O=C(O)c1cccnc1Oc1ccc2c(c1)OCO2
HCID2736879

2-[(2H-1,3-Benzodioxol-5-yl)oxy]pyridine-3-carboxylic acid

C13H9NO5

结构：N#Cc1cccc(Oc2ncccc2C(=O)O)c1
HCID12849335

2-(3-Cyanophenoxy)-3-pyridinecarboxylic acid

C13H8N2O3

结构：COC(=O)COc1ccc(CN)c(F)c1
HCID18174008

未命名化合物

结构：COC(=O)[C@@H](C)Oc1ccc(CN)c(F)c1
HCID60128049

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@H](C)Oc1ccc(CNC(=O)c2cccnc2Oc2cccc(C#N)c2)c(F)c1
HCID60128044

未命名化合物

PROCEDURE

实验过程

The compound of Formula (5.0.31) was prepared in a manner analogous to that described in Preparation 20, substituting 2-(3-cyano-phenoxy)-nicotinic acid and (R)-2-(4-aminomethyl-3-fluoro-phenoxy)-propionic acid methyl ester for the corresponding 2-(benzo-[1,3]-dioxol-5-yloxy)-nicotinic acid and (4-aminomethyl-3-fluoro-phenoxy)-acetic acid methyl ester materials, respectively.

WORKUP

后处理

  1. customthat described in Preparation 20