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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 350997생성일: 2026년 10월 25일

(+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl ester → (+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid

https://huagongshe.com/reaction/350997

반응식

참여 물질

역할이름HCID투입량
반응물(+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl esterHCID 23529359—
용매Formic AcidHCID 284—
생성물(+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acidHCID 1016119280.4%

반응 단계

(±)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro- phenoxy]-propionic acid tert-butyl ester (0.17 g, 0.33 mmol) was stirred in formic acid (5 mL) at room temperature 2 hours. Formic acid was removed in vacuo and the product stored over night under high vacuum to afford a white solid (0.12 g, 80% yield).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07183293B2
출처 데이터셋uspto-grants-2007_02
ORD IDord-634675a8015b4666968d8cdd5cb40b3f
출처 메모uspto-grants-2007_02