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HRID 350998作成日：2026年10月26日

(+/-)-2-[3-Fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid tert-butyl ester → (+/-)-2-[3-Fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid

https://huagongshe.com/reaction/350998

反応式

関与物質

役割名称HCID仕込み量
反応物(+/-)-2-[3-Fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid tert-butyl esterHCID 23529358—
反応物(+/-)-2-[4-({[2-(Benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl esterHCID 23529359—
生成物(+/-)-2-[3-Fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acidHCID 10137400—

反応手順

The compound of Formula (5.5.4) was prepared in a manner analogous to that described in Example 3, substituting (±)-2-[3-fluoro-4-({[2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl) -phenoxy]-propionic acid tert-butyl ester for the corresponding (±)-2-[4-({[2-(benzo[2,1,3]oxadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid tert-butyl ester material.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07183293B2
出典データセットuspto-grants-2007_02
ORD IDord-cd821a01e7dd4ce4afd36888aa6ef76a
出典メモuspto-grants-2007_02