HuagongsheHuagongshe Chemistry Print Report · For research reference only
CP-671305 → (R)-2-(Benzo[2,1,3]thiadiazol-5-yloxy)-N-[4-(1-carbamoyl-ethoxy)-2-fluoro-benzyl]-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | CP-671305 | HCID 9955578 | — |
| Reactant | (R)-2-[4-({[2-(Benzo[2,1,3]thiadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid | HCID 23529319 | — |
| Product | (R)-2-(Benzo[2,1,3]thiadiazol-5-yloxy)-N-[4-(1-carbamoyl-ethoxy)-2-fluoro-benzyl]-nicotinamide | HCID 23529325 | — |
Reaction Steps
The compound of Formula (5.5.16) was prepared in a manner analogous to that described in Example 14, substituting (R)-2-[4-({[2-(benzo[2,1,3]thiadiazol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid for the corresponding (R)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07183293B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-84ab546f7e2740cdaedd0fe793d7ba13 |
| Source note | uspto-grants-2007_02 |