Sodium Hydroxide → 4-Hydroxyphenylsulfonic acid disodium salt

HRID 351020Notes

Reaction equation

HRID 351020 reaction equation
O.O.[Na+:3].[OH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([O-:14])(=[O:13])=[O:12])=[CH:7][CH:6]=1.[OH-].[Na+]>C1(C)C=CC=CC=1>[Na+:3].[Na+:3].[OH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([O-:14])(=[O:12])=[O:13])=[CH:7][CH:6]=1.[OH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([O-:14])(=[O:12])=[O:13])=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 23666329Sodium P-phenolsulfonate dihydrate

Product 1

HCID 195991314-Hydroxyphenylsulfonic acid disodium saltYield 126.5%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 4-hydroxybenzenesulfonic acid sodium salt dihydrate (20 g, 86 mmol) in 1N aqueous sodium hydroxide (86 mL, 86 mmol) is stirred and heated at 50–60° C. for 1 hour. The solution is concentrated in vacuo at 50° C. to give a solid. The solid is suspended in anhydrous toluene and concentrated in vacuo. This process is repeated twice. The solid is dried at 50° C. at high vacuum for 18 hours to give 21.34 g of 4-hydroxybenzenesulfonic acid disodium salt.

Workup

  1. temperatureheated at 50–60° C. for 1 hour
  2. concentrationThe solution is concentrated in vacuo at 50° C.
  3. customto give a solid
  4. concentrationconcentrated in vacuo
  5. customThe solid is dried at 50° C. at high vacuum for 18 hours

Sources & evidence

ORD record
ord-bfa9679dccda4c6384a65e667bc80767
Source dataset
uspto-grants-2007_02
Patent number
US07183304B2

Reaction notes

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