反应详情

A solution of 4-hydroxybenzenesulfonic acid sodium salt dihydrate (20 g, 86 mmol) in 1N aqueous sodium hydroxide (86 mL, 86 mmol) is stirred and heated at 50–60° C. for 1 hour. The solution is concentrated in vacuo at 50° C. to give a solid. The solid is suspended in anhydrous toluene and concentrated in vacuo. This process is repeated twice. The solid is dried at 50° C. at high vacuum for 18 hours to give 21.34 g of 4-hydroxybenzenesulfonic acid disodium salt.

1. temperatureheated at 50–60° C. for 1 hour
2. concentrationThe solution is concentrated in vacuo at 50° C.
3. customto give a solid
4. concentrationconcentrated in vacuo
5. customThe solid is dried at 50° C. at high vacuum for 18 hours