HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351059Generated: October 30, 2026
Dichloromethane → 3-[3-(Naphthalen-1-ylsulfamoyl)phenyl]-acryloyl Chloride
https://huagongshe.com/reaction/351059
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 3-[3-(Naphthalen-1-ylsulfamoyl)-phenyl]-acrylic acid | HCID 67019567 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 3-[3-(Naphthalen-1-ylsulfamoyl)phenyl]-acryloyl Chloride | HCID 73989402 | 99.8% |
Reaction Steps
To a suspension of 3-[3-(naphthalen-1-ylsulfamoyl)-phenyl]-acrylic acid (15d) (0.22 g, 0.62 mmol) in dichloromethane (2.5 ml) oxalyl chloride (0.16 ml, 1.86 mmol) and one drop of dimethylformamide were added. The reaction mixture was stirred at 40° C. for one hour and concentrated under reduced pressure to give crude title compound (0.23 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07183298B2 |
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| Source dataset | uspto-grants-2007_02 |
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| ORD ID | ord-eb5776f0e77a4c51a1705fb109988248 |
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| Source note | uspto-grants-2007_02 |
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