HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,4-Benzodiazepine → 4-Chloro-6-(4-methyl-1-piperazinyl)-1,2,dihydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,4-Benzodiazepine | HCID 148431 | — |
| Reactant | N-[2-(5-chloro-1-indolinyl)phenyl]-4-methyl-1-piperazinecarboxamide | HCID 13823362 | — |
| Product | 4-Chloro-6-(4-methyl-1-piperazinyl)-1,2,dihydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine | HCID 13823295 | — |
Reaction Steps
It is predicted that if the N-[2-(5-chloro-2,3-dihydro-1H-indol- 1-yl)phenyl]-4-methyl-1-piperazinecarboxamide of Example 12a is treated in the manner of Example 4c that 6-(4-methyl-1-piperazinyl)-4-chloro-1,2-dihydrobenzo[b]3,2,1-jk][1,4]benzodiazepine will be obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04764616 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-78bef05da8164498bd433b7b1cd83d7b |
| Source note | uspto-grants-1988_08 |