HCID 10220223, compound → HCID 10041520, compound

HRID 351113Notes

Reaction equation

HRID 351113 reaction equation
NC1SC2C3C(CC=2C=1[C:14]([NH2:16])=[O:15])=CC=CC=3.FC(F)(F)C(O)=O.[NH2:24][C:25]1[S:29][C:28]2[C:30]3[C:35]([CH2:36][CH2:37][C:27]=2[C:26]=1[C:40]([NH2:42])=[O:41])=[CH:34][CH:33]=[C:32]([O:38][CH3:39])[CH:31]=3>>[CH3:39][O:38][C:32]1[CH:31]=[C:30]2[C:35]([CH2:36][CH2:37][C:27]3[C:26]([C:40]([NH2:42])=[O:41])=[C:25]([NH:24][C:14]([NH2:16])=[O:15])[S:29][C:28]=32)=[CH:34][CH:33]=1

Participants

3

Reactant 2

HCID 10220223HCID 10220223, compoundHCID 69373056HCID 69373056, compound

Product 1

HCID 10041520HCID 10041520, compound

Procedure

The title compound was prepared by the same procedure as Example 2 except 2-amino-4H-indeno[1,2-b]thiophene-3-carboxylic acid amide was replaced with 2-amino-8-methoxy-4,5-dihydro-naphtho[1,2-b]thiophene-3 carboxylic acid amide trifluoroacetate to give the above title compound as brown solid. ESMS m/z: 318 [M+H]+.

Sources & evidence

ORD record
ord-2121a2a6589e4b8e91dc52541f0fadde
Source dataset
uspto-grants-2007_02
Patent number
US07183311B2

Reaction notes

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