反应详情

温度

80 °C

The compound obtained in Step A (32.2 mmol) is dissolved in glacial acetic acid (40 ml) and then 48.3 mmol of bromine are added. The mixture is heated at 80° C. for 2 hours and is then hydrolysed using ice-cold water. The precipitate obtained is filtered off, washed with water until a pH of 5–6 is obtained, and then dried and recrystallised.

1. customThe precipitate obtained
2. filtrationis filtered off
3. washwashed with water until a pH of 5–6
4. customis obtained
5. customdried
6. customrecrystallised