HCID 21090711, compound → HCID 21090701, compound

HRID 351208Notes

Reaction equation

CS(O[CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[N:18]([C:19]3[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=3)[N:17]=[C:16]([C:26]([F:29])([F:28])[F:27])[CH:15]=2)=[CH:10][CH:9]=1)(=O)=O.[C:30]1(=[O:40])[NH:34][C:33](=[O:35])[C:32]2=[CH:36][CH:37]=[CH:38][CH:39]=[C:31]12.[K]>>[Cl:25][C:22]1[CH:23]=[CH:24][C:19]([N:18]2[C:14]([C:11]3[CH:12]=[CH:13][C:8]([CH2:7][CH2:6][N:34]4[C:30](=[O:40])[C:31]5[C:32](=[CH:36][CH:37]=[CH:38][CH:39]=5)[C:33]4=[O:35])=[CH:9][CH:10]=3)=[CH:15][C:16]([C:26]([F:28])([F:27])[F:29])=[N:17]2)=[CH:20][CH:21]=1

Participants

Reactant 2

HCID 21090711HCID 21090711, compound

HCID 24194345Phthalimide potassium salt

Product 1

HCID 21090701HCID 21090701, compound

Conditions

Temperature: 80 °C

Procedure

A mixture of 2-{4-[1-(4-chlorophenyl)-3-(trifluorom ethyl)-1H-pyrazol-5-yl]phenyl}ethyl methanesulfonate obtained by Example 51 (3.2 g) and Potassium phthalimide (1.6 g) was stirred at 80° C. for 5 hrs.

Sources & evidence

ORD record: ord-b8f8fea3c87948109fbe4b4e32e4ca4e
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07183306B2

Reaction notes

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