HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-[4-(4,4,4-trifluoro-3-oxobutanoyl)-phenoxy]ethylcarbamate → tert-Butyl 2-{4-[1-(1,3-benzodioxol-5-yl)-3-(trifluoro-methyl)-1H-pyrazol-5-yl]phenoxy}ethylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-[4-(4,4,4-trifluoro-3-oxobutanoyl)-phenoxy]ethylcarbamate | HCID 21091173 | — |
| Reactant | (2H-1,3-Benzodioxol-5-yl)hydrazine--hydrogen chloride (1/1) | HCID 22291622 | — |
| Product | tert-Butyl 2-{4-[1-(1,3-benzodioxol-5-yl)-3-(trifluoro-methyl)-1H-pyrazol-5-yl]phenoxy}ethylcarbamate | HCID 21091159 | 56.7% |
Reaction Steps
The title compound (371.3 mg, 56.7%) was prepared from tert-butyl 2-[4-(4,4,4-trifluoro-3-oxobutanoyl)-phenoxy]ethylcarbamate obtained by Example 78-2 and 1-(1,3-benzodioxol-5-yl)hydrazine hydrochloride obtained by Example 83-1 in a similar manner to that of Example 78-3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07183306B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-826dda95a7ce48ce84fd6aa34b1d1e7e |
| Source note | uspto-grants-2007_02 |