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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351226Generated: October 31, 2026

Sodium Cyanate → N-(2-{4-[5-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenoxy}ethyl)urea

https://huagongshe.com/reaction/351226

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanateHCID 517096—
ReactantHCID 21090842HCID 21090842—
SolventEthanolHCID 702—
SolventWaterHCID 962—
ProductN-(2-{4-[5-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenoxy}ethyl)ureaHCID 21091111—

Reaction Steps

To a solution of 2-{4-[5-(4-methoxyphenyl)-3-(tri-fluoromethyl)-1H-pyrazol-1-yl]phenoxy}ethanamine hydrochloride obtained by Example 96 (200 mg) in water (10 ml) and ethanol (5 ml) was added sodium cyanate (314 mg) at room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07183306B2
Source datasetuspto-grants-2007_02
ORD IDord-a3c9ca9d29b540c2947d68678f0fa74f
Source noteuspto-grants-2007_02