Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butylcyclohexylamine → N-(4-tert-Butylcyclohexyl)-N'-(7-hydroxynaphthalen-1-yl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butylcyclohexylamine | HCID 79396 | — |
| 반응물 | (7-Hydroxy-naphthalen-1-yl)-carbamic acid phenyl ester | HCID 20090380 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | N-(4-tert-Butylcyclohexyl)-N'-(7-hydroxynaphthalen-1-yl)urea | HCID 18435880 | — |
반응 단계
4-tert-Butyl-cyclohexylamine (69 mg, 0.44 mmol) and (7-hydroxy-naphthalen-1-yl)-carbamic acid phenyl ester (125 mg, 0.44 mmol) were combined and stirred at ambient temperature in DMSO (3 mL) overnight. The product was purified by directly injecting the crude reaction onto a reverse phase prep-HPLC (90–10% water:acetonitrile gradient). The appropriate fractions were lyophilized to yield 1-(4-tert-Butyl-cyclohexyl)-3-(7-hydroxy-naphthalen-1-yl)-urea
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07183411B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-75db14825a1f48a6961e36069b97b72c |
| 출처 메모 | uspto-grants-2007_02 |