Iodine chloride → 2,3,2'-Trifluoro-4-iodo-4''-propyl-[1,1';4',1'']-terphenyl

HRID 351358Notes

Reaction equation

HRID 351358 reaction equation
C[Si](C)(C)[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][CH3:23])=[CH:17][CH:16]=3)=[CH:11][C:10]=2[F:24])=[C:5]([F:25])[C:4]=1[F:26].[I:29]Cl>C(#N)C>[F:25][C:5]1[C:4]([F:26])=[C:3]([I:29])[CH:8]=[CH:7][C:6]=1[C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][CH3:23])=[CH:17][CH:16]=2)=[CH:11][C:10]=1[F:24]

Participants

4

Reactant 2

HCID 24640Iodine chlorideHCID 11153756Trimethyl-(2,3,2'-trifluoro-4''-propyl-[1,1';4',1'']-terphenyl-4-yl)silane

Product 1

HCID 112479632,3,2'-Trifluoro-4-iodo-4''-propyl-[1,1';4',1'']-terphenylYield 54%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

The total amount of the terphenyl 9 is dissolved in 4 ml of absolute acetonitrile and reacted with 1.2 ml (6 mmol) of a 5 M solution of ICl in acetonitrile, and the mixture is stirred at room temperature for 1 hour. The residue is crystallised at −20° C. for 2 hours. The supernatant solution is subsequently sucked off, and the product which remains is washed with 2 M Na2S2O5 (10 ml) and water (10 ml) and dried in an oil-pump vacuum (yield: 54%).

Workup

  1. customThe residue is crystallised at −20° C. for 2 hours
  2. washthe product which remains is washed with 2 M Na2S2O5 (10 ml) and water (10 ml)
  3. customdried in an oil-pump vacuum (yield: 54%)

Sources & evidence

ORD record
ord-6e771a48a909446c851a68618caf4438
Source dataset
uspto-grants-2007_02
Patent number
US07183447B2

Reaction notes

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