Maleic Anhydride → HCID 18436361, compound

Participants

Reaction Steps

To the solution of 2,3-di(4-methoxyphenyl)-1,3-butadiene (2.1 g) in toluene (30 mL) was added maleic anhydride (3.8 g, 5.0 eq.) and the reaction mixture refluxed for 6 h. The reaction mixture was then diluted with ethyl acetate (500 mL) and was washed with water (3×200 mL). The organic layer was dried and concentrated to yield 5,6-bis-(4-methoxy-phenyl)-3a,4,7,7a-tetrahydro-isobenzofuran-1,3-dione.

Provenance & Evidence