HRID351605

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)C(=O)c1cn2c3c(cc(F)cc13)C(C)(C)CC2

HCID69743463

未命名化合物

结构：CC(C)(C)OC(=O)C1Cn2ccc3c(CC(N)=O)ccc(c32)CN1

HCID69745709

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)C1Cn2ccc3c(C4=C(c5cn6c7c(cc(F)cc57)C(C)(C)CC6)C(=O)NC4=O)ccc(c32)CN1

HCID69900598

未命名化合物

PROCEDURE

实验过程

Beginning with 7-Carbamoylmethyl-3,4-dihydro-1H-[1,4]diazepino[6,7,1-hi]indole-2-carboxylic acid tert-butyl ester and (8-Fluoro-6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-oxo-acetic acid methyl ester, the title compound was prepared essentially as Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9f1b80554d684146b4fcd91454a63d75
来源数据集: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06743785B2
来源说明: uspto-grants-2004_06

反应 SMILES

[C:1]([O:5][C:6]([CH:8]1[NH:20][CH2:19][C:17]2=[C:18]3[C:13](=[C:14]([CH2:21][C:22](=[O:24])[NH2:23])[CH:15]=[CH:16]2)[CH:12]=[CH:11][N:10]3[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C[O:26][C:27](=O)[C:28]([C:30]1[C:40]2=[C:41]3[C:36](=[CH:37][C:38]([F:42])=[CH:39]2)[C:35]([CH3:44])([CH3:43])[CH2:34][CH2:33][N:32]3[CH:31]=1)=O>>[C:1]([O:5][C:6]([CH:8]1[NH:20][CH2:19][C:17]2=[C:18]3[C:13](=[C:14]([C:21]4[C:22](=[O:24])[NH:23][C:27](=[O:26])[C:28]=4[C:30]4[C:40]5=[C:41]6[C:36](=[CH:37][C:38]([F:42])=[CH:39]5)[C:35]([CH3:43])([CH3:44])[CH2:34][CH2:33][N:32]6[CH:31]=4)[CH:15]=[CH:16]2)[CH:12]=[CH:11][N:10]3[CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]