HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Ethoxycarbonyl-1-(2-fluorbenzyl)-1H-pyrazolo-(3,4,5)-pyridin | HCID 11162345 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide | HCID 11323178 | — |
Reaction Steps
10.18 g (34 mmol) of the ester from Example 21A are initially charged in 150 ml methanol which has been saturated with ammonia at 0-10° C. The mixture is stirred at room temperature for two days and subsequently concentrated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06743798B1 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-1063409872dc4c5ebcd1391019e20e17 |
| Source note | uspto-grants-2004_06 |