Cyclohexanol → cyclohexyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 35168Notes

Reaction equation

HRID 35168 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH:18]1([OH:24])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:24][CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 7966CyclohexanolHCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

Product 1

HCID 20041718cyclohexyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Procedure

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and cyclohexanol there is obtained cyclohexyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate as a resinous product, 1H-NMR(CDCl3): 1.1-2.3 (10H), 4.21 (s, 4H), 4.75 (m, OCH), 4.95 (broad s, NH), 7.3-7.7 (8H);

Sources & evidence

ORD record
ord-d50ec6c8dd7441509fa95d285c5096cd
Source dataset
uspto-grants-1988_08
Patent number
US04766115

Reaction notes

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