proline dl-form → 1-(4-Fluoro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid isopropyl ester

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The title compound was prepared from DL-proline, isopropanol, and 4-fluorobezenesulfonyl chloride according to the procedure of Intermediate 48 as a clear oil; 1H NMR (CDCl3) δ 1.21-1.28 (m, 6H), 1.80-1.85 (m, 1H), 1.95-2.10 (m, 3H), 3.31-3.49 (m, 2H), 4.26-4.36 (m, 1H), 4.95-5.08 (m, 1H), 7.15-7.23 (m, 2H), 7.89-8.08 (m, 2H); MS (ES) m/z 315.8 (MH+); HRMS for C14H18FNO4S: 338.0830 (M+Na)

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