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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351738Generated: October 25, 2026

3-Bromoquinoline → HCID 10226356, compound

https://huagongshe.com/reaction/351738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromoquinolineHCID 21413—
Reactant3-Hydroxy-3-phenyl-1-butyneHCID 92098—
Reactant1-(3-bromophenyl)-N-isopropyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamideHCID 12991318—
ProductHCID 10226356HCID 10226356—

Reaction Steps

Following the procedure of EXAMPLE 15, but substituting N-isopropyl-1-(3-ethynylphenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide from Step 2 of EXAMPLE 5 for 2-phenyl-3-butyn-2-ol, and 3-bromoquinoline for N-isopropyl-1-(3-bromophenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide, the title compound was obtained as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06743802B2
Source datasetuspto-grants-2004_06
ORD IDord-058daf43f4e44aa88f5ef26b42ef0cd2
Source noteuspto-grants-2004_06