Hydrazine → HCID 14230058, compound

HRID 35186Notes

Reaction equation

HRID 35186 reaction equation
[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[C:9]([C:12](=O)[CH2:13][CH2:14][C:15]([OH:17])=O)[CH:10]=[CH:11][C:5]=2[S:4][CH2:3]1.[NH2:19][NH2:20]>C(O)C>[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[C:9]([C:12]3[CH2:13][CH2:14][C:15](=[O:17])[NH:19][N:20]=3)[CH:10]=[CH:11][C:5]=2[S:4][CH2:3]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 142300624-(3,4-Dihydro-3-oxo-1,4[2H]-benzothiazin-6-yl)-4-oxobutyric acid

Product 1

HCID 14230058HCID 14230058, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-(3,4-Dihydro-3-oxo-1,4[2H]-benzothiazin-6-yl)-4-oxobutyric acid (2.0 g) was suspended in 60 ml of ethanol and 1 ml of hydrazine added. The mixture was heated at reflux for three hours, then cooled slowly. Filtration gave 1.85 g of the title compound, mp 299°-302° C.

Workup

  1. temperatureThe mixture was heated
  2. temperatureat reflux for three hours
  3. temperaturecooled slowly
  4. filtrationFiltration

Sources & evidence

ORD record
ord-6479d54947d345759c6a43ca703d3118
Source dataset
uspto-grants-1988_08
Patent number
US04766118

Reaction notes

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