HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → Ethyl 3-phenyl-3-[6-(4-hydroxybutoxy)indol-3-yl]propionate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 4-Bromobutanol | HCID 118388 | — |
| Edukt | Ethyl 3-phenyl-3-(6-hydroxyindol-3-yl)propionate | HCID 15549281 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | Ethyl 3-phenyl-3-[6-(4-hydroxybutoxy)indol-3-yl]propionate | HCID 22714487 | — |
Reaktionsschritte
Analogously to Example 1.4, 1.2 g (3.88 mmol) of ethyl 3-phenyl-3-(6-hydroxyindol-3-yl)propionate are reacted with 1.16 g (7.6 mmol) of 4-bromo-1-butanol in the presence of 2.1 g (15.2 mmol) of potassium carbonate in 30 ml of acetone, giving ethyl 3-phenyl-3-[6-(4-hydroxybutoxy)indol-3-yl]propionate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06743810B2 |
| Quelldatensatz | uspto-grants-2004_06 |
| ORD ID | ord-bdbe467bff3347989743f13f1d11a32d |
| Quellennotiz | uspto-grants-2004_06 |