反应详情

5 g (47 mmol) of anhydrous sodium carbonate are added to a solution of 10.0 g (47 mmol) of n-tetradecylamine in 100 ml of absolute acetone, and the suspension is heated to reflux. At that temperature 5.9 g (50 mmol) of propargyl bromide in 50 ml of acetone are then added dropwise and the mixture is subsequently heated at reflux for 2 hours. After aqueous working-up, the product is obtained in the form of a brown oil having a purity of >90%.

1. temperaturethe suspension is heated to reflux
2. temperaturethe mixture is subsequently heated
3. temperatureat reflux for 2 hours
4. customAfter aqueous working-up, the product is obtained in the form of a brown oil