HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylethyl 4-(hydroxyimino)-4-phenylbutylcarbamate → tert-butyl N-(4-amino-4-phenylbutyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylethyl 4-(hydroxyimino)-4-phenylbutylcarbamate | HCID 73993156 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-butyl N-(4-amino-4-phenylbutyl)carbamate | HCID 16795070 | 107.6% |
Reaction Steps
1,1-Dimethylethyl 4-(hydroxyimino)-4-phenylbutylcarbamate (2.3 g, 8.3 mmol), in absolute ethanol was hydrogenated over 10% palladium on charcoal (0.5 g) at 5 bar pressure for 20 h. The mixture was then filtered and the filtrate concentrated to dryness to afford the title compound as a colourless oil (2.36 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06743939B2 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-67fc204a87ee4cd9ade8e6b1f0e75ae7 |
| Source note | uspto-grants-2004_06 |