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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352142Generated: October 29, 2026

4-Chloro-2-hydroxybenzonitrile → [4-(5-Chloro-2-cyanophenoxy)-4-(2-thiazolyl)butyl]carbamic acid 1,1-dimethylethyl ester

https://huagongshe.com/reaction/352142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-hydroxybenzonitrileHCID 3442789—
Reactant[4-Hydroxy-4-(2-thiazolyl)butyl]carbamic acid 1,1-dimethylethyl esterHCID 131724450—
Product[4-(5-Chloro-2-cyanophenoxy)-4-(2-thiazolyl)butyl]carbamic acid 1,1-dimethylethyl esterHCID 70153671—

Reaction Steps

The subtitle compound was prepared according to the method of Example 19 step (b) using the product of step (c) above and 2-hydroxy-4-chlorobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06743939B2
Source datasetuspto-grants-2004_06
ORD IDord-1c59f2ead2204902a9b7db3fc3e0ad46
Source noteuspto-grants-2004_06