Boron tribromide → HCID 86587319, compound

Participants

Reaction Steps

2 g of the 2,3,5,6-tetrafluoro-4-methoxyphenylmaleimide obtained in Example 1 was dissolved in 10 ml of dry methylene chloride. Thereto was added 15 ml of a methylene chloride solution containing 1 M of boron tribromide. The mixture was stirred at room temperature for 3 days in an argon atmosphere. The reaction mixture was poured into 200 ml of ice water. The organic layer was extracted with ether. The ether layer was washed with an aqueous sodium chloride solution and dried over magnesium sulfate. The resulting solution was subjected to vacuum distillation to remove ether. The residue was recrystallized from ligroin/toluene to obtain 1 g of an intended compound (yield: 53%).

Provenance & Evidence