HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene → 2-Propyl-1,2,3,4-tetrahydro-6-naphthol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene | HCID 22709051 | — |
| Reactant | 2-Propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol | HCID 22709064 | — |
| Solvent | 2-Propyl-1,2,3,4-tetrahydronaphthalen-6-yl trifluoromethanesulfonate | HCID 22709045 | — |
| Product | 2-Propyl-1,2,3,4-tetrahydro-6-naphthol | HCID 11240938 | — |
| Product | 2-Propyl-7-fluoro-1,2,3,4-tetrahydro-6-naphthol | HCID 22709032 | — |
Reaction Steps
Syntheses were performed in the same manner as (7-2) and (7-3), with the exception of using the 2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol and the 2-propyl-7-fluoro-1,2,3,4-tetrahydro-6-naphthol obtained in (10-1) above instead of the 2-propyl-1,2,3,4-tetrahydro-6-naphthol in (7-2), and yielded 35 g of 2-propyl-5-fluoro-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene, and 53 g of 2-propyl-7-fluoro-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06746728B1 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-f4778caf0dc54cbfb39b8dce6cb44ce3 |
| Source note | uspto-grants-2004_06 |