HCID 69837885, compound → HCID 44402878, compound

Participants

Reaction Steps

A solution of D6 (380 mg, 0.64 mmole) in EtOH (50 ml) and THF (50 ml) was treated with 10% Pd-C (300 mg) and stirred under a hydrogen atmosphere at ambient temperature and pressure for 70 h. The mixture was filtered through Kieselguhr and concentrated under vacuum. The residue was purified by chromatography on basic alumina eluting with EtOAc followed by crystallisation from Et2O to afford the title compound as a yellow solid (320 mg, 98%). MH+507.

Provenance & Evidence