2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 9890607, compound

Participants

Reaction Steps

A solution of E8 (1.8 g, 3.86 mmole) in DCM (150 ml) was treated with a solution of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (908 mg, 4.0 mmole) in DCM (50 ml) and the mixture stirred at room temp. under argon for 20 mins. The mixture was washed with 10% Na2CO3 solution, dried (Na2SO4), and evaporated to a brown oil. Column chromatography on silica gel (eluent 5% MeOH/DCM) afforded the title compound as a yellow semi-solid (1.1 g, 61%), which was converted to its hydrochloride salt as a white solid.

Provenance & Evidence