2-(4-Chloro-3-nitrophenyl)-2-methylpropanoic acid → 2-(3-Aminophenyl)-2-methylpropanoic acid hydrochloride

Participants

Reaction Steps

In 50 ml of methanol was dissolved 10.0 g of 2-(4-chloro-3-nitrophenyl)-2-methylpropionic acid. To the resulting mixture was added 1.0 g of 10% palladium carbon. In a hydrogen gas atmosphere, the mixture was stirred at room temperature for 3 hours. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure to obtain 8.84 g of the title compound.

Provenance & Evidence