Trifluoroacetic acid → HCID 9828699, compound

Participants

Reaction Steps

A solution of (3S)-3-{3-[(1S)-1-phenylmethyloxycarbonylamino-2-methyl-propyl]-5-phenoxymethyl-4,5-dihydro-isoxazole-5-carbonyl-amino}-4-keto-pentanoic acid t-butyl ester (less polar diastereomer) (44 mg) in CH2Cl2 (2 mL) at 0° C. was treated with TFA (1 mL). The reaction mixture was stirred for 2 h while slowly warming to room temperature. Concentration gave the title compound (compound 10, quantitative).

Provenance & Evidence