tert-Butyl piperazine-1-carboxylate → 1-[(E)-4-Chlorostyrylsulfonyl)piperazine hydrochloride

HRID 352733Notes

Reaction equation

HRID 352733 reaction equation
[N:1]1(C(OC(C)(C)C)=O)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:26]=[CH:25][C:18](/[CH:19]=[CH:20]/[S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[ClH:14].[Cl:14][C:15]1[CH:16]=[CH:17][C:18](/[CH:19]=[CH:20]/[S:21]([N:1]2[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]2)(=[O:23])=[O:22])=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 5938154(E)-2-(4-chlorophenyl)ethene-1-sulfonyl chloride

Product 1

HCID 227103861-[(E)-4-Chlorostyrylsulfonyl)piperazine hydrochloride

Procedure

In the same manner as in Referential Example 1, a reaction was conducted using tert-butyl 1-piperazinecarboxylate and (E)-4-chlorostyrylsulfonyl chloride as starting materials, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-785231e5c6854e8cbf251fee88aa5554
Source dataset
uspto-grants-2004_06
Patent number
US06747023B1

Reaction notes

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