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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352740Generated: October 25, 2026

4-Pyridin-3-yl-benzoic acid → 4-tert-Butoxycarbonyl-2-ethoxycarbonyl-1-[4-(3-pyridyl)benzoyl]piperazine

https://huagongshe.com/reaction/352740

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pyridin-3-yl-benzoic acidHCID 1515244—
Reactant1-tert-Butyl 3-ethyl piperazine-1,3-dicarboxylateHCID 11402671—
Product4-tert-Butoxycarbonyl-2-ethoxycarbonyl-1-[4-(3-pyridyl)benzoyl]piperazineHCID 17796471—

Reaction Steps

In the same manner as in Referential Example 12, a reaction was conducted using 4-(3-pyridyl)benzoic acid and 1-tert-butoxycarbonyl-3-ethoxycarbonylpiperazine as starting materials, whereby the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06747023B1
Source datasetuspto-grants-2004_06
ORD IDord-e8ae6db69c474385ac7dd1e619ff5203
Source noteuspto-grants-2004_06