[1-(tert-Butoxycarbonyl)piperidin-4-yl]acetic acid → HCID 22709906, compound

HRID 352749Notes

Reaction equation

HRID 352749 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][C:15]([OH:17])=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[Cl:19][C:20]1[CH:21]=[C:22]2[C:27](=[CH:28][CH:29]=1)[CH:26]=[C:25]([S:30]([N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)(=[O:32])=[O:31])[CH:24]=[CH:23]2>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][C:15]([N:36]2[CH2:35][CH2:34][N:33]([S:30]([C:25]3[CH:24]=[CH:23][C:22]4[C:27](=[CH:28][CH:29]=[C:20]([Cl:19])[CH:21]=4)[CH:26]=3)(=[O:32])=[O:31])[CH2:38][CH2:37]2)=[O:17])[CH2:12][CH2:13]1)=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Procedure

In the same manner as in referential Example 12, a reaction was conducted using (1-tert-butoxycarbonylpiperidin -4-yl)acetic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as starting materials, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-2b8211b9a67d45e5ab23bed675c5c4db
Source dataset
uspto-grants-2004_06
Patent number
US06747023B1

Reaction notes

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