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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352750Generated: October 30, 2026

3-(1-((Tert-butoxy)carbonyl)piperidin-4-yl)propanoic acid → 1-[3-(1-tert-Butoxycarbonylpiperidin-4-yl]propionyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine

https://huagongshe.com/reaction/352750

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(1-((Tert-butoxy)carbonyl)piperidin-4-yl)propanoic acidHCID 1512540—
Reactant1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochlorideHCID 22709766—
Product1-[3-(1-tert-Butoxycarbonylpiperidin-4-yl]propionyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazineHCID 22709824—

Reaction Steps

In the same manner as in Referential Example 12, a reaction was conducted using 3-(1-tert-butoxycarbonylpiperidin-4-yl)propionic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]-piperazine hydrochloride as starting materials, whereby the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06747023B1
Source datasetuspto-grants-2004_06
ORD IDord-95b465cafd4a40f2a21f4124ec1f2a65
Source noteuspto-grants-2004_06