1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride → HCID 22709865, compound

HRID 352907Notes

Reaction equation

HRID 352907 reaction equation
[OH:1][C:2]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.Cl.[Cl:18][C:19]1[CH:20]=[C:21]2[C:26](=[CH:27][CH:28]=1)[CH:25]=[C:24]([S:29]([N:32]1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1)(=[O:31])=[O:30])[CH:23]=[CH:22]2>>[ClH:18].[Cl:18][C:19]1[CH:20]=[C:21]2[C:26](=[CH:27][CH:28]=1)[CH:25]=[C:24]([S:29]([N:32]1[CH2:33][CH2:34][N:35]([C:4](=[O:6])[C:3]3[CH:7]=[CH:8][C:9]([C:11]4[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=4)=[CH:10][C:2]=3[OH:1])[CH2:36][CH2:37]1)(=[O:30])=[O:31])[CH:23]=[CH:22]2

Participants

3

Reactant 2

HCID 227097661-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochlorideHCID 22710668HCID 22710668, compound

Product 1

HCID 22709865HCID 22709865, compound

Procedure

In the same manner as in Example A-4, a reaction was conducted using 2-(hydroxy-4-(4-pyridyl)benzoic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as starting materials, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-913b3ba8e50b4fb9aff54bf8091d332f
Source dataset
uspto-grants-2004_06
Patent number
US06747023B1

Reaction notes

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