HCID 22710088, compound → HCID 22710792, compound

HRID 352950Notes

Reaction equation

HRID 352950 reaction equation
[CH3:1][CH:2]1[NH:7][CH2:6][C:5]2[S:8][C:9]([C:11]([O-:13])=O)=[N:10][C:4]=2[CH2:3]1.[Li+].FC(F)(F)C(O)=O.[Cl:22][C:23]1[CH:24]=[C:25]2[C:30](=[CH:31][CH:32]=1)[CH:29]=[C:28]([S:33]([N:36]1[CH2:41][CH2:40][NH:39][CH:38]([C:42]([N:44]3[CH2:49][CH2:48][O:47][CH2:46][CH2:45]3)=[O:43])[CH2:37]1)(=[O:35])=[O:34])[CH:27]=[CH:26]2>>[ClH:22].[Cl:22][C:23]1[CH:24]=[C:25]2[C:30](=[CH:31][CH:32]=1)[CH:29]=[C:28]([S:33]([N:36]1[CH2:41][CH2:40][N:39]([C:11]([C:9]3[S:8][C:5]4[CH2:6][NH:7][CH:2]([CH3:1])[CH2:3][C:4]=4[N:10]=3)=[O:13])[CH:38]([C:42]([N:44]3[CH2:45][CH2:46][O:47][CH2:48][CH2:49]3)=[O:43])[CH2:37]1)(=[O:34])=[O:35])[CH:27]=[CH:26]2

Participants

3

Reactant 2

HCID 22710088HCID 22710088, compoundHCID 23674323Lithium 6-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate

Product 1

HCID 22710792HCID 22710792, compound

Procedure

Starting materials: lithium 6-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate, 4-[[1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazin-3-yl]carbonyl]morpholine trifluoroacetate

Sources & evidence

ORD record
ord-52d8b84c3104474eba58889898894076
Source dataset
uspto-grants-2004_06
Patent number
US06747023B1

Reaction notes

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