Nitric Acid → 2-(Methylthio)-6-nitro-1,3-benzothiazole

Participants

Reaction Conditions

Reaction Steps

See FIG. 4A. Fuming nitric acid (1.93 g) was added dropwise to a solution of 2-(methylthio)benzothiazole (5 g) in concentrated sulfuric acid (16.8 g) cooled in an ice bath. After stirring at 5° C. for 3 h the solution was poured onto ice and filtered to provide a yellow solid (5.7 g, 25 mmol, 91%).

Provenance & Evidence