Bromine → HCID 22708245, compound

HRID 353194Notes

Reaction equation

HRID 353194 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.Br[C:10]([CH2:20][CH3:21])([CH2:18][CH3:19])[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12].BrN1C(=O)CCC1=O.BrBr>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:10]([CH2:18][CH3:19])([CH2:20][CH3:21])[C:11]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:12])=[CH:4][CH:3]=1

Participants

5

Reactant 4

HCID 24408BromineHCID 660494-BromothiophenolHCID 67184N-bromobutanimideHCID 22708277HCID 22708277, compound

Product 1

HCID 22708245HCID 22708245, compound

Procedure

The synthesis was carried out similarly to Example II-1 from 4-bromothiophenol and 1,1-dimethylethyl 2-bromo-2-ethyl-butanoate [preparation, for example, similarly to Liebigs Ann. Chem. 725, 106-115 (1969); J. Am. Chem. Soc. 77, 946-947 (1955), and bromination with N-bromosuccinimide or bromine, for example similarly to Tetrahedron Lett. 1970, 3431; J. Org. Chem. 40, 3420 (1975)].

Workup

  1. custompreparation

Sources & evidence

ORD record
ord-7645995b866b49f5a00c1f794a7b65fb
Source dataset
uspto-grants-2004_06
Patent number
US06750236B2

Reaction notes

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