Cesium carbonate → HCID 69891893, compound

Participants

Reaction Steps

To a solution of 5-hydroxyindole (0.25 g) in acetonitrile (10 mL) was added cesium carbonate (1.22 g) and cinnamyl bromide (0.37 g). The suspension was stirred under nitrogen at ambient temperature overnight. Cesium salts were removed by filtration and washed with acetone. The residue left on concentrating the combined filtrate and washings was chromatographed over silica eel with a mixture of ethyl acetate and hexanes and crystallized from ether with hexanes to give 0.23 g of the title compound. MS CI (MH+)=250

Provenance & Evidence