HCID 131724418, compound → HCID 131724417, compound

HRID 353405Notes

Reaction equation

HRID 353405 reaction equation
[N+:1]([C:4]1[CH:23]=[C:22]([C:24]2[C:29]([I:30])=[C:28]([N:31]([CH3:35])[C:32](=[O:34])[CH3:33])[C:27]([I:36])=[C:26]([N:37]([CH3:41])[C:38](=[O:40])[CH3:39])[C:25]=2[I:42])[CH:21]=[C:20]([N+:43]([O-])=O)[C:5]=1[C:6]([C:8]1([O:17][C@H:16]([CH2:18][OH:19])[C@@H:14]([OH:15])[C@H:12]([OH:13])[C@H:10]1[NH2:11])[OH:9])=[O:7])([O-])=O.[H][H]>[Pd]>[NH2:43][C:20]1[CH:21]=[C:22]([C:24]2[C:25]([I:42])=[C:26]([N:37]([CH3:41])[C:38](=[O:40])[CH3:39])[C:27]([I:36])=[C:28]([N:31]([CH3:35])[C:32](=[O:34])[CH3:33])[C:29]=2[I:30])[CH:23]=[C:4]([NH2:1])[C:5]=1[C:6]([C:8]1([O:17][C@H:16]([CH2:18][OH:19])[C@@H:14]([OH:15])[C@H:12]([OH:13])[C@H:10]1[NH2:11])[OH:9])=[O:7]

Participants

4

Reactant 2

HCID 131724418HCID 131724418, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 131724417HCID 131724417, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

2,6-dinitro-4-[3′,5′-bis(N-methylacetamido)-2′,4′,6′-triiodophenyl]-benzoyl-D-glucosamine (15) is catalytically reduced by hydrogen in the presence of palladium on charcoal to yield 2,6-diamino-4-[3′,5′-bis(N-methylacetamido)-2′,4′,6′-triiodophenyl]-benzoyl-D-glucosamine (16).

Sources & evidence

ORD record
ord-79ea19f5264445d4b2a5c00e921b80a5
Source dataset
uspto-grants-2004_06
Patent number
US06751290B2

Reaction notes

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