Bromotrimethylsilane → HCID 22644540, compound

Participants

Reaction Steps

0.2 mol trimethylsilylbromide are slowly added to a solution of 0.1 mol 3-(N-hydroxyamino)-propionylphosphonic acid dimethylester in 100 ml of absolute acetonitrile. After 3 hours of stirring at room temperature the solution is concentrated and taken up in 50 ml methanol. After stirring for 30 minutes it is concentrated again. 3-(N-hydroxyamino)-propionylphosphonic acid may be further be converted without purification.

Provenance & Evidence