5-Hydrazinylquinoline → Methyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylate

Participants

Role	Name	HCID	Charge
Reactant	5-Hydrazinylquinoline	HCID 5200451	—
Reactant	alpha-[(Dimethylamino)methylene]-beta-oxo-cyclopropanepropanoic Acid Methyl Ester;Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)acrylate; Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)prop-2-enoate	HCID 11401341	—
Product	Methyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylate	HCID 11449248	—

Reaction Steps

combining 5-hydrazinoquinoline made by a method of this invention with α-[(dimethylamino)methylene]-β-oxo-cyclopropanepropanoic acid, (αZ)-methyl ester to form 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester; and

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06753334B2
Source dataset	uspto-grants-2004_06
ORD ID	ord-ee23e13c85b4417682adaeb3e6c3ce62
Source note	uspto-grants-2004_06