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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 353441Generated: October 29, 2026

5-Hydrazinylquinoline → Methyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylate

https://huagongshe.com/reaction/353441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-HydrazinylquinolineHCID 5200451—
Reactantalpha-[(Dimethylamino)methylene]-beta-oxo-cyclopropanepropanoic Acid Methyl Ester;Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)acrylate; Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)prop-2-enoateHCID 11401341—
ProductMethyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylateHCID 11449248—

Reaction Steps

combining 5-hydrazinoquinoline made by a method of this invention with α-[(dimethylamino)methylene]-β-oxo-cyclopropanepropanoic acid, (αZ)-methyl ester to form 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06753334B2
Source datasetuspto-grants-2004_06
ORD IDord-ee767bdea267434493065a7d8a314720
Source noteuspto-grants-2004_06