反应详情

Two 500 ml-capacity reaction vessels were kept at a reduced pressure of 240 Torr. To the first reaction vessel were fed a 33.3% by weight of an aqueous solution of diacetone-L-sorbose at a rate of 150 g/hour, and a 5% by weight of an aqueous solution of nickel chloride at a rate of 3 ml/hour, and a 12.5% by weight aqueous solution of sodium hypochlorite at a rate as shown in Table 2, with a constant volume pump. The reaction mixture boiled at a temperature of 70° C. After 6 hours from the start of feeding of the reactants, the effluent from the second reaction vessel was sampled for 1 hour, and was worked up in the same manner as in Example 1, to provide diacetone-2-keto-L-gulonic acid.

1. customboiled at a temperature of 70° C
2. aliquotthe effluent from the second reaction vessel was sampled for 1 hour