1-Bromo-2-butyne → Ethyl{[3-(2-butynyloxy)phenyl]sulfanyl}acetate

HRID 353538Notes

Reaction equation

HRID 353538 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([S:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:5]=[CH:6][CH:7]=1.Br[CH2:16][C:17]#[C:18][CH3:19]>>[CH2:13]([O:12][C:10](=[O:11])[CH2:9][S:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([O:1][CH2:16][C:17]#[C:18][CH3:19])[CH:3]=1)[CH3:14]

Participants

3

Reactant 2

HCID 27568621-Bromo-2-butyneHCID 57418561Ethyl [(3-hydroxyphenyl)sulfanyl]acetate

Product 1

HCID 23513827Ethyl{[3-(2-butynyloxy)phenyl]sulfanyl}acetateYield 100%

Procedure

Ethyl{[3-(2-butynyloxy)phenyl]sulfanyl}acetate was prepared according to the general method as outlined in example 1 (step 2), starting from ethyl [(3-hydroxyphenyl) sulfanyl]acetate (3.87 g, 18.3 mmol) and 4-bromo-2-butyne (2.66 g, 20 mmol); 5.16 g yellow oil. Yield 100%; MS(EI): 264.1 (M+H)+.

Sources & evidence

ORD record
ord-768e6c62af5c421ba2fdc104a370a15b
Source dataset
uspto-grants-2004_06
Patent number
US06753337B2

Reaction notes

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