Sodium borohydride → [4-(4-Ethylpiperazin-1-yl)phenyl]methanol

HRID 353601Notes

Reaction equation

HRID 353601 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([C:9]2[CH:16]=[CH:15][C:12]([CH:13]=[O:14])=[CH:11][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].[BH4-].[Na+]>C(O)C>[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([C:9]2[CH:16]=[CH:15][C:12]([CH2:13][OH:14])=[CH:11][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 105130244-(4-ethylpiperazin-1-yl)benzaldehyde

Product 1

HCID 23514389[4-(4-Ethylpiperazin-1-yl)phenyl]methanol

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This compound was prepared in the manner of Step A, Example 5, using 0.4 gram (0.019 mole) of [4-(4-ethylpiperazinyl)benzaldehyde and 0.4 gram (0.01 mole) of sodium borohydride in 40 mL of absolute ethanol (available from J. T. Baker Inc.) The yield of the title compound was 0.3 gram. The NMR Spectrum was consistend with the proposed structure.

Workup

  1. customThis compound was prepared in the manner of Step A, Example 5

Sources & evidence

ORD record
ord-302113a3c76744a8a46dde3f6efb1c7d
Source dataset
uspto-grants-2004_06
Patent number
US06753429B2

Reaction notes

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