Benzamide → Methyl (5-methyl-2-phenyl-1,3-oxazol-4-yl)acetate

HRID 353664Notes

Reaction equation

Br[CH:2]([CH3:11])/[C:3](/OC)=[CH:4]\[C:5]([O:7][CH3:8])=[O:6].[C:12]([NH2:20])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH3:11][C:2]1[O:19][C:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:20][C:3]=1[CH2:4][C:5]([O:7][CH3:8])=[O:6]

Participants

Reactant 2

HCID 2331Benzamide

HCID 59977658methyl (E)-4-bromo-3-methoxy-pent-2-enoate

Product 1

HCID 2775318Methyl (5-methyl-2-phenyl-1,3-oxazol-4-yl)acetate

Procedure

reacting methyl (E)-4-bromo-3-methoxy-pent-2-enoate with benzamide to give methyl 2-(5-methyl-2-phenyl-4-oxazolyl)acetate,

Sources & evidence

ORD record: ord-6fe142d0419848788c0028f47160676d
Source dataset: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06753432B2

Reaction notes

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