HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 10176594, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-(5-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetic acid | HCID 853753 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10176594 | HCID 10176594 | — |
Reaction Steps
Oxalyl chloride (6.3 g, 50 mmol) is added dropwise over 5 minutes to a solution of 1-(carboxymethyl)thymine (9.2 g, 50 mmol) dissolved in dichloromethane (200 mL). The reaction is stirred until gas evolution has ceased and then for an additional 2 hours. The reaction mixture is evaporated to an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06756199B1 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-3abc123402bb4163b0b5f42ef617c02b |
| Source note | uspto-grants-2004_06 |