HCID 178476666, compound → HCID 178476664, compound

Participants

Reaction Steps

The aforementioned 3,6-bis(dimethylamino)-9-(2-acetoxymethoxycarbonyl-3-amino-4-nitrophenyl)xanthylium bromide (443 mg) was dissolved in a mixed solvent of ethanol (100 ml) and dichloromethane (100 ml), and the solution was added with 0.25 g of 10% Pd/C catalyst. The mixture was stirred at room temperature under a hydrogen atmosphere for 2 hours. The reaction mixture was filtered, and the solvent was evaporated. The residue was purified by silica gel column chromatography to obtain 3,6-bis(dimethylamino)-9-(2-acetoxymethoxycarbonyl-3,4-diaminophenyl)xanthylium bromide (214 mg, 50.9%).

Provenance & Evidence